IndraLab

Statements

Guanosine inhibits PAN2. 4 / 4
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eidos
"Caf1 shows strict specificity for poly ( A ) and is inhibited by all non-A nucleotides , whereas Pan2 is substantially inhibited only by guanosines at the end of a poly ( A ) tail ( Fig. 3A , B ) ."
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sparser
"Caf1 shows strict specificity for poly(A) and is inhibited by all non-A nucleotides, whereas Pan2 is substantially inhibited only by guanosines at the end of a poly(A) tail ( xref )."
32295929
sparser
"To understand why guanosines inhibit Pan2, we soaked AAGGA or AAGGAA RNAs into Pan2 UCH-Exo crystals, which diffracted to 3.3 Å resolution ( xref )."
31110294
reach
"Strikingly, this two-color deadenylation assay showed that one guanosine was sufficient to inhibit Pan2."
31110294