IndraLab

Statements

UCHL3 decreases the amount of COPS5. 2 / 2

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"We found that UCHL3 knockdown noticeably upregulated ubiquitination levels of COPS5."

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"Since COPS5 have been demonstrated to downregulate Cullin1 neddylation and activity, we speculate that UCHL3 could downregulate the activity of SCF beta and TrCP complex by upregulating cellular COPS5[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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INDRA sources:

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IndraLab

Statements

UCHL3 decreases the amount of COPS5. 2 / 2

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