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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP29 decreases the amount of SIRT1. 2 / 2

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"Based on these results, we demonstrate that USP29 inhibits SIRT1 expression via the p53/miR-34a axis."

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"As shown in Figures 4(a)–4(d), USP29 inhibition did not affect cerebral SIRT3 expression upon I/R injury but restored cerebral I/R-induced downregulation of SIRT1, while USP29 overexpression further decreased SIRT1 expression in I/R-injured brains."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...