IndraLab

Statements


USP1 inhibits CDKN1A. 2 / 2
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"Taken together, our results demonstrate that USP1 suppresses p21 via ID protein stabilization and inhibition of bHLH transcriptional activity in osteosarcoma.Osteosarcomas are heterogeneous tumors com[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"shRNA resistant wild-type USP1, but not USP1 C90S, reduced p21 to levels observed in control cells, confirming knockdown specificity in this setting."