Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP1 inhibits CDKN1A. 2 / 2

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"Taken together, our results demonstrate that USP1 suppresses p21 via ID protein stabilization and inhibition of bHLH transcriptional activity in osteosarcoma.Osteosarcomas are heterogeneous tumors com[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"shRNA resistant wild-type USP1, but not USP1 C90S, reduced p21 to levels observed in control cells, confirming knockdown specificity in this setting."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...