IndraLab

Statements


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reach
"USP3 leads to activation of the PI3K/AKT signaling pathway in OS by binding to EPHA2, then reducing protein degradation."

sparser
"USP3 binds to and deubiquitinates EPHA2."

sparser
"Moreover, R203 of USP3 was important during the interaction between USP3 and EPHA2, and K882 and K945 of EPHA2 were the key ubiquitination sites regulated by USP3."