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Genome polyprotein increases the amount of USP19. 14 / 14
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"Taken together, ERβ agonists seem to have a generally beneficial effect on muscle mass, but might exert distinct effects on E2-induced USP19 expression."
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"Daidzein activated ERβ-dependent transcriptional activity in vitro, and inhibited E2-induced USP19 mRNA expression in vitro and in vivo ."
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"E2 induced ubiquitin specific peptidase 19 (USP19) expression during myogenesis."
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"Furthermore, in skeletal muscle satellite cells, E2 inhibited myogenesis and increased USP19 expression, and diarylpropionitrile repressed E2 increased USP19 expression."
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"Ogawa et al. report that E2 treatment of ovx mice decreased the ratio of skeletal muscle mass to body weight and increased ubiquitin-specific peptidase 19 expression, indicating that E2 inhibits myogenesis in vivo."
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"Administration of E2 to OVX mice decreased muscle mass ratio and increased USP19 mRNA expression in the soleus muscle of OVX mice."
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"Likely, in OVX mice, E2 up-regulated USP19 protein expression, and daidzein attenuated E2-dependent increase of USP19 protein expression ( Fig. 5 D)."
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"These results indicate that in soleus muscle of OVX mice, daidzein inhibits the E2-dependent increase in USP19 expression through ERβ and the E2-depdentnt decrease in muscle ratio.USP19 expression is [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Additionally, under physiological conditions in young female mice, E2 induces USP19 expression through ERα, and knockdown of either ERα or USP19 increases soleus muscle mass by inducing muscle hypertr[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Also, an E2 dose-dependent increase in USP19 mRNA expression was observed in the myoblast cell line C2C12 [ 47 ]."
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"These results demonstrate that in soleus muscle in young female mice under physiological conditions, E2 upregulates USP19 expression through ERalpha and consequently leads to decreases in ubiquitin conjugates and muscle mass."
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"E2 replacement increased USP19 expression in the gastrocnemius and soleus muscles of ovariectomized mice."
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"Propylpyrazole-triol increased USP19 expression, and ICI 182,780 inhibited E2 increased USP19 expression."
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"We previously reported that E2 induces the recruitment of ERα to the hERE of the Usp19 gene and up-regulates USP19 expression at the mRNA level in the soleus muscle of female mice, but not in male mic[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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