IndraLab

Statements


E2 increases the amount of USP19. 5 / 5
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"Furthermore, in skeletal muscle satellite cells, E2 inhibited myogenesis and increased USP19 expression, and diarylpropionitrile repressed E2 increased USP19 expression."

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"Propylpyrazole-triol increased USP19 expression, and ICI 182,780 inhibited E2 increased USP19 expression."

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"E2 replacement increased USP19 expression in the gastrocnemius and soleus muscles of ovariectomized mice."

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"These results demonstrate that in soleus muscle in young female mice under physiological conditions, E2 upregulates USP19 expression through ERalpha and consequently leads to decreases in ubiquitin conjugates and muscle mass."

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"E2 induced ubiquitin specific peptidase 19 (USP19) expression during myogenesis."