IndraLab

Statements


OTUD3 is phosphorylated on S326. 2 / 2
| 2

sparser
"Furthermore, PLK1 mediates OTUD3 S326 phosphorylation, which further enhances OTUD3 binding and deubiquitination of YY1."

sparser
"Phosphorylation status also affects transcriptional regulation, such as PLK1-mediated Ser326 phosphorylation of OTUD3, which stabilizes YY1 and supports tumor growth [ xref ], or the downregulation of PCYT2, which reduces YAP1 phosphorylation, enhancing metastasis through SNAIL2 and ZEB1 activation [ xref ]."