IndraLab

Statements

MiR-96 activates SCN3A. 2 / 2
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"Moreover, daily intrathecal injections of miR-96 restored Nav1.3 mRNA and protein levels in DRG of injured rats and significantly reduced tactile allodynia."
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"In a recent study, miR-183 and miR-96 were observed a significant down-regulation with the increase of Nav1.3 expression in L5 DRG after SNL, which were abundant in DRG neurons (Aldrich et al., 2009; Lin et al., 2014), overexpression of miR-183 and miR-96 were capable to attenuate neuropathic pain by repressing Nav1.3."
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