IndraLab

Statements


Ataxia3 mutant activates SCN8A. 1 / 1
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"The failure of the ataxia3 mutant to rescue the motor abnormalities and lethality of a null allele of Scn8a, together with the phenotypic similarity of ataxia3 to Scn8a mutants and the genetic mapping of ataxia3 near Scn8a, strongly support the identification of Nav1.6-S21P as the causal mutation in ataxia3 mice."