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USP8 decreases the amount of MMP9. 2 / 2
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"Moreover, USP8 knockdown decreased the expression and activity of MMP9, MMP2, and N-cadherin, while it increased the expression of TIMP-1, TIMP-2, and E-cadherin ( Fig. 3 G)."

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"In addition, the overexpression of USP8 reversed the decreased expression of MMP9, MMP2, and N-cadherin and high protein expression of TIMP-1, TIMP-2, and E-cadherin that was induced by SCNN1A silenci[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"