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4-(ethoxymethylene)-2-phenyloxazol-5-one inhibits STAT1. 2 / 2

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"p47 phox deficiency in T cells diminished the expression of transcription factors STAT1, STAT4, and T-bet and reduced the production of cytokine, such as IL-2, IL-4, IFN-gamma, TNF-alpha, and GM-CSF [XREF_BIBR]."

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"The oxazolone induced pSTAT1 response was inhibited by orally dosed tofacitinib (1-30mg/kg) by up to 88 +/-5% (mean +/- SEM) when dosed 3h after intrarectal oxazolone."

29225517

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IndraLab

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4-(ethoxymethylene)-2-phenyloxazol-5-one inhibits STAT1. 2 / 2

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