IndraLab

Statements


Mutated BAP1 activates olaparib. 2 / 2
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"A BAP1 mutant by alternative splicing resulting in a 54-bp deletion increased sensitivity to the PARP inhibitor olaparib."

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"Mutant BAP1 in combination with CCDC6 silencing enhanced the HR-DNA repair defects and sensitivity to olaparib."