IndraLab

Statements



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"JOSD2 also stabilizes YAP/TAZ to promote cholangiocarcinoma progression [6]."

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"Another study revealed that JOSD2 promoted cholangiocarcinoma proliferation by deubiquitinating and stabilizing Yes-associated protein (YAP) and transcriptional co-activator with PDZ-binding motif (TAZ), two essential transcriptional co-activators of the Hippo pathway ."

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"Deubiquitinase JOSD2 stabilizes YAP/TAZ to promote cholangiocarcinoma progression."

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"For instance, USP36 deubiquitinates ALKBH5 to facilitate the progression of glioblastoma [9], and JOSD2 stabilizes YAP/TAZ to enhance the advancement of cholangiocarcinoma [8]."

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"Another study suggests YAP/TAZ is stabilized by the JOSD2 deubiquitinase to promote cholangiocarcinoma progression [ 25 ]."