IndraLab

Statements


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"Taken together, USP35 plays a vital role in resistance to cisplatin-induced cell death through the overexpression of BIRC3."

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"We previously showed that deubiquitinase USP35 and ERalpha act in a positive feedback loop to promote the carcinogenesis of ER+ breast cancer although it is unclear whether USP35 regulates cell death in ER+ breast cancer."

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"To further explore the mechanism of USP35 action in ER+ breast cancer, we investigated whether USP35 promotes the growth of ER+ breast cancer by inhibiting cell death."