IndraLab

Statements

OTUD1 decreases the amount of MAVS. 5 / 5
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"In this study, we uncovered that OTUD1 can downregulate protein levels of MAVS, TRAF3 and TRAF6."
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"OTUD1 negatively regulates protein levels of MAVS, TRAF3, and TRAF6."
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"In this process, OTUD1 negatively regulates the protein levels of mitochondrial antiviral-signaling protein (MAVS) and the TNF receptor-associated factor 3 (TRAF3) and TRAF6 E3s."
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"OTUD1 negatively regulates MAVS protein levels by the upregulation of Smurf1 (Figure 4A)."
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"Together, these data suggest that OTUD1 negatively regulates protein levels of MAVS, TRAF3, and TRAF6."
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