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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

COPS6 activates CUL. 2 / 2

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"We find that CSN6 enhanced Cullin neddylation facilitates auto-ubiquitination and degradation of Myc E3 ligase Fbxw7, thereby stabilizing Myc, indicates that CSN6 is a positive upstream regulator of Myc."

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"CSN6 competes with CSN5 to increase Cullin neddylation."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...