IndraLab

Statements

USP7 activates ERK. 4 / 4
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"Surprisingly, the USP7 knockdown suppressed the activation of ERK1/2 along with an increase in p53 protein level in A549 cells."
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"Moreover, USP7 siRNA blocked the activation of Akt/ERK signaling pathway."
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"These results indicate that the knockdown of USP7 inhibits the ERK1/2 signaling pathway via a p53-dependent mechanism."
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"In OSCC cells, USP7 was shown to promote cell proliferation, inhibit apoptosis, enhance cell migration and invasion, and activate the Akt/ERK pathway."
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