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VEGFA activates NRP2. 4 / 4
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"In lung adenocarcinoma cells, HH/GLI signaling is upregulated by stromal VEGF-A mediated stimulation of NRP2 [23]."
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"VEGF-A induces intracellular signaling by binding to one of two receptors: VEGF receptor-1 (VEGFR-1, previously termed fms-like tyrosine kinase-1 [Flt-1]) and VEGFR-2 (previously termed murine fetal l[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Interestingly, we showed that blocking of VEGFA prevents CM dependent activation of EPHB2 and NRP2, among others."
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"In this study, we show that both VEGF-A and VEGF-C induce the interaction of NRP2 with VEGFR-2."
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