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P5091 activates Colitis. 2 / 2
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"Notably, the USP7 inhibitor, P5091, inhibits oxidative stress and colitis in vivo."

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"As shown in Figure 6B–D, P5091‐treated mice with DSS‐induced colitis presented with alleviated colitis, which manifested as longer colon length, lower spleen weight, and lower disease activity index (DAI) scores than those treated with PBS."