IndraLab

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USP42 increases the amount of CDKN1A. 2 / 2
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"As we had demonstrated before, USP42 knockdown lowers p21 transcription at the early time points of p53 induction as a reflection of the reduced levels of p53."

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"For example, USP36 promotes transcriptional repression of Cyclin Dependent Kinase Inhibitor 1A ( CDKN1A ; also known as P21 ) by removing H2Bub1 specifically within the transcribed region, while USP42[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"