IndraLab

Statements

USP47 ubiquitinates NLRP3. 4 / 4
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reach
"The relationship among ZNF883, miR-138-5p, and USP47 as well as the regulation of NLRP3 ubiquitination by USP47 was determined."
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reach
"Chemical inhibition of DUBs USP7 and USP47 increases the ubiquitination of NLRP3, prevents PYCARD oligomerization and speck formation, and blocks inflammasome formation [130]."
36551253
sparser
"Chemical inhibition of DUBs USP7 and USP47 increases the ubiquitination of NLRP3, prevents PYCARD oligomerization and speck formation, and blocks inflammasome formation [ xref ]."
36551253
reach
"A previous study revealed that USP7 and USP47 activated NLRP3 inflammasome by regulating ASC oligomerization, NLRP3 ubiquitination, and speck formation in macrophages, but remained unclear whether USP7 and USP47 contributed to NLRP3 deubiquitination directly or indirectly [32]."
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