IndraLab

Statements

Type I IFNs increases the amount of USP18. 3 / 3
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"16 Both USP18 expression and conjugation of ISG15 are strongly induced by viral infections and type I IFNs, XREF_BIBR, XREF_BIBR suggesting that protein modifications by USP18 regulated ISG15 have a role in responses to viruses and type I IFN signaling."
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"In innate cells, it has been reported that type I IFNs or viral infection induces expression of Usp18."
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"USP18 gene expression has been found at low levels in multiple tissues and cell lines and could be rapidly up-regulated by type I IFNs."
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