IndraLab

Statements


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"Because MLN4924 inhibits the alternative NFkappaB pathway downstream of IKK1 at the level of p100 processing, the quite discordant effects between MLN4924 and BAY 11-7082 must thus be due to blockade of IKK1 mediated NFkappaB independent necrosis-inhibitory functions or represent an off-target effect of BAY 11-7082."