IndraLab

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ATM activates USP28. 3 / 4
1 | 2 1

reach
"In line with this model, our data indicate that ATM-dependent activation of USP28 stimulates origin firing early after genotoxic stress."

reach
"Since 5 '-AZA treatment can activate ATM in AML cells and the ATM pathway can prevent the apoptosis induction in 5 '-AZA resistant cells XREF_BIBR, we sought to determine whether ATM modulated the effect of USP28 on the UCK1 deubiquitination in response to 5 '-AZA."

sparser
"In line with this model, our data indicate that ATM-dependent activation of USP28 stimulates origin firing early after genotoxic stress."