IndraLab

Statements


TSPYL5 inhibits USP7. 2 / 2
| 2

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"These observations suggest that TSPY1 and TSPYL5 can induce USP7 degradation via the 26S proteasome system."

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"USP7 is the deubiquitylase for the p53 tumour suppressor and TSPYL5 reduces the activity of USP7 towards p53, resulting in increased p53 ubiquitylation."