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OTUB1 binds TNF. 2 / 2
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"OTUB1 can directly bind tumor necrosis factor receptor-associated factor 6 (TRAF6), inhibit its lysine 63-linked polyubiquitination, and thus inhibit the activation of apoptotic signal-regulated kinas[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"The deubiquitinating enzyme ubiquitin aldehyde binding 1 (OTUB1) directly binds to tumor necrosis factor receptor-associated factor 6 (TRAF6) and inhibits its lysine 63-linked polyubiquitination, thereby inhibiting the activation of ASK1 and its downstream MAPK pathway 73.The ubiquitin system also plays an important role in the activation of other pathways."
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