IndraLab

Statements


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sparser
"As shown in Figure  xref , we identified 8 L‐R pairs—COL15A1‐ITGA1, EDIL3‐ITGB5, LAMA4‐ITGAV, SEMA3D‐NRP1, SEMA3D‐PLXND1, TGFB1ITGB8, TGFB1‐TGFBR1 and TGFB2‐TGFBR1—that are conserved across at least three of the four diseases."

sparser
"Mechanistic studies indicated that ITGB8-TGFβ1 axis modulates VM and epithelial-mesenchymal transition (EMT) process via Smad2/3-RhoA signaling."

sparser
"Our study showed that ITGB8-TGFβ1 affected downstream activation of Smad2/3 and RhoA in glioma cells."

sparser
"Furthermore, we identified upregulated TGFB1-ITGB8 signaling from microglia to astrocytes, suggesting a potential increasing microgliogenesis in the sEOAD EC and PFC xref ."

sparser
"Previous studies have shown that ITGB8 could interact with TGF-β1 at the fetomaternal interface during early pregnancy []."

reach
"Previous studies have shown that ITGB8 could interact with TGF-beta1 at the fetomaternal interface during early pregnancy [35]."

sparser
"We identified a single ligand-receptor pair from both astrocytes and microglia to oligodendrocytes with a high ligand activity: TGFB1-ITGB8 ( xref )."