IndraLab

Statements

USP13 activates PTEN. 6 / 10
| 6
reach
"USP13 mediates PTEN to ameliorate osteoarthritis by restraining oxidative stress, apoptosis and inflammation via AKT dependent manner."
33378983
reach
"Previous studies have shown that knockdown of USP13 reduces PTEN, and over-expression of USP13 results in higher levels of PTEN [18]."
37634814
reach
"These data supported our notion that USP13 suppresses tumorigenesis by blocking the NF-kB-driven PTEN downregulation in BC."
31200745
reach
"Researchers attributed a tumor suppressor role to USP13 gene by showing that USP13 mediates PTEN signaling in different types of cancers (15–17)."
35583846
reach
"USP13 increases PTEN stability [126] , whereas USP7 reverses monoubiquitylation and nuclear accumulation of PTEN [125] ."
24704338
reach
"Similarly, Jing Geng et al. found that inhibition of USP13-mediated PTEN protein loss caused phenotypic changes in fibroblasts and impacted the pathogenesis of IPF."
38017523