IndraLab

Statements



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"In support of this, we found that palmitate induced inflammatory gene expression was substantially reduced in MyD88 deficient macrophages compared with that in control cells, while completely abolished in TLR4 -/- and partially impaired in TLR2 -/- macrophages, suggesting the possible role of saturated fatty acids (SFAs) in promoting TLR-MyD88-dependent switching of ATMs from M2- to M1 like inflammatory macrophages (unpublished data)."

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"We found that palmitate treatment did not induce degradation of MyD88 and TRIF even in Cbl-b +/+ peritoneal macrophages."

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"However, palmitate treatment did not induce degradation of MyD88 and TRIF, even in Cbl-b +/+ peritoneal macrophages (XREF_FIG)."