IndraLab

Statements

EIF3F activates TP53. 4 / 8
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"qRT-PCR revealed that eIF3f did not stimulate the upregulation of p53 mRNA, suggesting that eIF3f does not inhibit p53 levels."
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"EIF3f increases the stability of p53."
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"These results suggest that eIF3f promotes the tumor suppressor function of p53 by increasing the stability of p53 protein."
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"EIF3f overexpression activates p53 and Bax and inhibits Akt and ERK signaling."
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