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EMMAA Bob with Bioagents

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

EIF3F activates TP53. 4 / 8

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"qRT-PCR revealed that eIF3f did not stimulate the upregulation of p53 mRNA, suggesting that eIF3f does not inhibit p53 levels."

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"EIF3f increases the stability of p53."

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"These results suggest that eIF3f promotes the tumor suppressor function of p53 by increasing the stability of p53 protein."

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"EIF3f overexpression activates p53 and Bax and inhibits Akt and ERK signaling."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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