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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

PSMD14 deubiquitinates TGFB. 2 / 2

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"In hepatocellular carcinoma, PSMD14 enhanced the activation of TGF-beta signaling and tumor metastasis by deubiquitinating TGF-beta receptors and caveolin-1 XREF_BIBR."

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"Mechanistically, POH1 deubiquitinates the TGF-beta receptors and CAV1, therefore negatively regulates lysosome pathway mediated turnover of TGF-beta receptors."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...