IndraLab

Statements


CYLD inhibits RLR. 2 / 2
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reach
"On the other hand, deubiquitinating enzymes (DUBs), such as DUBA XREF_BIBR, CYLD XREF_BIBR, XREF_BIBR and OTUB1/2 XREF_BIBR have been shown to negatively regulate RLR signaling by specifically removing K63 linked polyubiquitin chains from several signaling molecules."

eidos
"Firstly , CYLD was shown to remove K63-linked ubiquitin chains from RIG-I , TBK1 , and IKKepsilon under basal conditions , thereby inhibiting RLR signaling [ 67,68 ] ."