IndraLab

Statements



reach
"We further show increased anti-parasite immunity driven by dysregulation of Treg by CYLD deletion."

reach
"The inhibition of CYLD and/or A20 could enhance the inflammatory or immune response, but the prolonged consequences are unclear and await assessment in animal models and in early clinical trials."

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"In E. coli induced pneumonia, CYLD has been shown to negatively regulate the immune response by blocking PAMP (Pathogen Associated Molecular Pattern)-induced NF-kB activation [XREF_BIBR]."