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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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CYLD inhibits immune response. 3 / 3

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"We further show increased anti-parasite immunity driven by dysregulation of Treg by CYLD deletion."

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"The inhibition of CYLD and/or A20 could enhance the inflammatory or immune response, but the prolonged consequences are unclear and await assessment in animal models and in early clinical trials."

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"In E. coli induced pneumonia, CYLD has been shown to negatively regulate the immune response by blocking PAMP (Pathogen Associated Molecular Pattern)-induced NF-kB activation [XREF_BIBR]."

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CYLD inhibits immune response. 3 / 3

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