IndraLab

Statements


SCN9A activates PE. 2 / 2
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"Other mutations in SCN9A associated with more negative activation thresholds are known to cause primary erythermalgia (PE)."

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"PE is exclusively caused by mutations in SCN9A, the encoding gene of sodium channel subtype Nav1.7 and can be sub-classified into familial (inherited erythromelalgia) and sporadic forms."