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SRC inhibits KCNH1. 2 / 2
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"These results suggest that the EGFR kinase inhibitor AG556, but not PDGFR kinase inhibitor AG1295 or the Src family kinase inhibitor PP2, inhibits hEAG1 current in HEK cells stably expressing hEAG1 ge[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
22061963
reach
"We found that the selective epidermal growth factor receptor (EGFR) kinase inhibitor AG556 (10 muM), but not the platelet growth factor receptor (PDGFR) kinase inhibitor AG1295 (10 muM) or the Src family inhibitor PP2 (10 muM), can inhibit hEAG1 current, and the inhibitory effect can be reversed by the protein tyrosine phosphatase (PTP) inhibitor orthovanadate."
22061963