IndraLab
Statements
Brefeldin A inhibits JUN. 2 / 2
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2
sparser
"Additional ARF GEFs, namely BIG1 (BREFELDIN A-INHIBITED GUANINE NUCLEOTIDE-EXCHANGE PROTEIN 1), BIG2/BEN3 (BFA-VISUALIZED ENDOCYTIC TRAFFICKING DEFECTIVE 3), BIG3, BIG4 and BIG5/BEN1/MIN7 (HOPM1 INTERACTOR 7) have been assigned various roles in guiding endosomal trafficking and vesicular sorting of PINs along the trans-Golgi network/early endosomal route xref , xref – xref ."
sparser
"Interestingly, a search on PhosphoSitePlus database indicates that multiple GEFs, including Brefeldin-Resistant Arf-GEF 2 (BRAG2, IQSEC1), Brefeldin A-Inhibited Guanine Nucleotide-Exchange Protein 1 (BIG1), and Cytohesin 2 (ARNO), can be phosphorylated on the tyrosine analogous to Y876 ( xref )."