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USP10 decreases the amount of SKP2. 2 / 2
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"Unsurprisingly, Diosmetin can reduce the protein level of Sp1, but have no effect on the protein level of USP10, which supports that Diosmetin inhibits transcription of SKP2 rather than promoting its [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"To our expectation, pharmacological inhibition of USP10 by Spautin-1 significantly increased the poly-ubiquitination level of SKP2."