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OTUD7B inhibits pathway. 3 / 3
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"A previous study showed that OTUD7B can inhibit the NF-κB pathway in liver cancer [ xref ]."
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"To examine the potential mechanism by which OTUD7B inhibits the LCL161-induced NF-κB pathway, we transfected Flag-TRAF3 and HA-OTUD7B, Myc-NIK and HA-OTUD7B into H1299 cells for 48 h."
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"Previous studies have shown that OTUD7B inhibited NF-κB pathway by deconjugating K63-polyubiquitin chains from RIP-1 and TRAF6, suggesting that it may have roles in inhibition of cancer progression xref , xref ."
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