IndraLab

Statements

USP36 binds COPS3. 3 / 3
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sparser
"Mechanistically, anakinra appears to have prevented SOD2 degradation by interfering with the USP36-COPS3 complex rather than inducing its expression."
34207085
sparser
"The induction of SOD2 was selective, as other antioxidant enzymes did not appear to be modulated by anakinra, as occurs for other SOD2 mimetics, an effect that may be related to the ability of anakinra to interfere with the USP36-COPS3 complex, rather than engaging the Nrf2 pathway [ xref ]."
34207085
sparser
"Anakinra Prevents SOD2 Degradation via USP36-COPS3."
34207085