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USP43 decreases the amount of CTTN. 2 / 2
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"The addition of MG132 successfully rescued the decrease of cortactin expression caused by USP43 knock-down (Fig. 5F), while the addition of CHX resulted in more unstable cortactin protein in USP43 knock-down cells (Fig. 5G)."
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"Knock-down of USP43 in MDA-MB-231 cells decreased the expression of cortactin at the protein level (Fig. 5B) but did not affect its transcript (Fig. 5C)."
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