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USP48 binds SIRT6 and K48. 3 / 3
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"USP48 physically binds and stabilizes SIRT6 by K48-linked deubiquitination to impede glucose metabolic reprogramming and hamper HCC tumorigenesis.Lipids include phospholipids, fatty acids, triglycerid[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"USP48 physically bound and stabilized SIRT6 by K48 linked deubiquitination at the K33 and K128 sites of SIRT6, which impeded metabolic reprogramming to hamper HCC tumorigenesis."

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"Du et al. described that after being stabilized by methyltransferase-like 14 (Mettl14), USP48 binds and stabilizes SIRT6 by K48-linked deubiquitination of this SIRT (K33/K128)."