IndraLab

Statements

reach
"The results showed that scutellarin dose-dependently reduced caspase-1 activation and decreased mature interleukin-1beta (IL-1beta) release in lipopolysaccharide (LPS)-primed macrophages upon ATP or nigericin stimulation, indicating that scutellarin inhibited NLRP3 inflammasome activation in macrophages."
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reach
"Consistent with these studies, our results showed that scutellarin not only inhibited caspase-1 activation and pyroptosis but also blocked mature IL-1beta secretion into culture supernatants."
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