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USP13 leads to the dephosphorylation of AKT. 2 / 2
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"The deubiquitinating enzyme USP13 increases PTEN protein stability and inhibits Akt phosphorylation, suppressing tumourigenesis and glycolysis in breast cancer (BC) [42] ."

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"6 The PTEN protein level was increased and the phosphorylation of AKT (p-AKT) was reduced by the overexpression of USP13 (Figure 2F)."