IndraLab

Statements

USP53 activates Neoplasms. 3 / 3
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"The overexpression of USP53 in TNBC promotes the deubiquitination of CRKL and tumor growth and metastasis in TNBC."
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"As shown, the knockdown of USP53 significantly reduced the proliferation of mouse mammary tumors (Figure 2m)."
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"In addition, USP53 overexpression significantly decreased the percentage of Ki-67+ proliferating cells and increased that of TUNEL + apoptotic cells in the tumor tissues compared to the control (Fig. 3G–I)."
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