Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Ubiquitin inhibits USP8. 2 / 2

| 2

➶

reach

"When we overexpressed Usp8 in ESCs, the ubiquitin modification of EPG5 decreased, while reduced Usp8 expression increased EPG5 ubiquitination (Fig. 5a, b)."

30931944

➶

reach

"These data indicate that under ischemic conditions, Nrdp1 upregulation may hinder the stabilization of HIF-1alpha in neurons via promoting ubiquitin mediated degradation of USP8, thus attenuating cellular adaptive response to hypoxia and ischemia."

28979191

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...