IndraLab

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IC 50 inhibits KCNH2. 3 / 3
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"Such noncardiovascular drugs included antipsychotics which block HERG with different degree of block : the concentrations required to produce 50% block of HERG (IC 50) were in nanomolar range for sert[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Published IC 50 values for the inhibition of hERG by these compounds in hERG patch clamp analysis allowed the comparison of the results from this study to patch clamp analysis."

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"Carvedilol inhibited HERG current in a concentration-dependent manner, IC 50 is 0.51 µM ( Kawakami et al., 2006 )."