IndraLab

Statements

His-Ser inhibits NLRP3. 5 / 5
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"Moreover, HS also inhibited the formation of NLRP3 and ASC specks and maintained the interaction of HSP70 with NLRP3 under nigericin treatment."
30874540
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"In this context, there arises an interesting question required to be addressed by future work, that is, whether HRS possesses the ability to inhibit the presumed HS induced activation of NLRP3 during the development of pancreatitis."
25214720
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"Heat Shock (HS) inhibits NLRP3 inflammasome activation in vitro and in vivo."
30874540
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"This HS induced activation of the NLRP3 inflammasome was significantly blocked by MSC transplantation into the renal medulla in Dahl S rats."
26764201
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"The nucleotide binding, leucine rich repeat and pyrin domain containing 3 (NLRP3) inflammasome was decreased by HS and further lowered by PFA-C400, but the nucleotide binding oligomerization domain, leucine rich repeat, and CARD domain containing 3 (NLRC3) and nucleotide binding, leucine rich repeat containing X1 (NLRX1) inflammasomes were increased by PFA under TN conditions, with no effects of HS."
33518325