IndraLab

Statements

OTUD5 activates TNF-α production. 4 / 4
| 4
reach
"Given that DUBA deubiquitinates K63-liked polyubiquitination of TRAF3 and thereby inhibits type I IFN responses, the administration of DUBA ASOs is likely to augment the NF-κB dependent TNF-α production."
37700847
reach
"In contrast to this hypothesis, Dinnalo’s data suggest that DUBA is an inducer of TNF-α production."
37700847
reach
"Up-regulation of OTUD5 further increased TNF-α production in LPMCs of IBD patients (160)."
34956195
reach
"Knockdown of DUBA expression by its antisense oligonucleotides reduces TNF-α production by colonic lamina propria mononuclear cells isolated from mice challenged with intrarectal TNBS administration (74)."
39403381