IndraLab

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USP12 translocates from the cytoplasm to the nucleus. 11 / 11
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"Furthermore, we found that in IFN signaling USP12 translocates from the cytoplasm to the nucleus."
31899788
sparser
"USP12 translocates from the cytoplasm to the nucleus in IFN signaling."
31899788
reach
"Mechanistically, USP12 translocates from the cytoplasm to the nucleus and blocks the CREB-binding protein (CBP)-induced acetylation of phosphorylated STAT1 (p-STAT1), thereby maintaining the nuclear p-STAT1 levels and IFN antiviral activity [21]."
37410794
sparser
"To our surprise, we observed that during mIFNβ treatment, cytoplasmic USP12 protein levels dramatically decreased and nuclear USP12 protein levels increased accordingly ( xref ), suggesting that USP12 translocates from the cytoplasm to the nucleus in IFN signaling."
31899788
sparser
"For example, USP12 is described above as promoting NF-κB activation for NLRP3 inflammatory microsome production, but in NSCLC it inhibits NF-κB signaling activity and regulates chemokine secretion by deubiquitinating and stabilizing PPM1B. Apart from that, USP12 can translocate from the cytoplasm to the nucleus during signaling to function in maintaining nuclear p-STAT1 levels and IFN antiviral efficacy."
37752518
reach
"Apart from that, USP12 can translocate from the cytoplasm to the nucleus during signaling to function in maintaining nuclear p-STAT1 levels and IFN antiviral efficacy."
37752518
reach
"The recent studies showed that USP12 translocated from the cytoplasm to the nucleus in IFN signaling [ 18 ]."
35032679
sparser
"To our surprise, in IFN signaling USP12 translocates from the cytoplasm to the nucleus."
31899788
sparser
"Mechanistically, USP12 translocates from the cytoplasm to the nucleus and blocks the CREB-binding protein (CBP)-induced acetylation of phosphorylated STAT1 (p-STAT1), thereby maintaining the nuclear p-STAT1 levels and IFN antiviral activity [ xref ]."
37410794
sparser
"The recent studies showed that USP12 translocated from the cytoplasm to the nucleus in IFN signaling [ 18 ]."
35032679
reach
"Furthermore, we found that in IFN signaling USP12 translocates from the cytoplasm to the nucleus."
31899788