IndraLab

Statements


ATP inhibits TBK1. 2 / 2
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"To pursue targeting TBK1 by pharmacological inhibition, we used BX795, an ATP competitive inhibitor of TBK1."

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"ATP depletion causes suppression of Na -K pump (Na/K-P) activity, thereby resulting in oncotic cell swelling due to an impairment of the pump-leak balance (P-LB) mechanism (Okada et al., 2021a; Tosteson and Hoffman, 1960)."